Lp(a)

Wako Product Name

Autokit Lp(a)

For In Vitro Diagnostic Use

• Detects Various Isoforms of Lp(a)
• No cross-reactivity to Apo B or plasminogen
• Formatted for most automated analyzers
• Excellent stability
• Reagents ready to use

The Wako Autokit Lp(a) test is an in vitro diagnostic assay for the quantitative determination of lipoprotein (a) in serum or plasma to aid, in conjunction with other lipoprotein tests, with the risk assessment of coronary artery disease (CAD).

Components of Lp(a) have similarities to both LDL and plasminogen, suggesting that Lp(a) may represent a bridge between the fields of atherosclerosis and thrombosis. Numerous studies suggested an association of plasma Lp(a) concentrations with atherosclerotic vascular disease. There are numerous techniques for measuring Lp(a) such as radial immunodiffusion (RID), radioimmunoassay (RIA), enzyme-linked immunoassay (ELISA), nephelometric immunoassay (NIA), and turbidimetric immunoassay (TIA). The Wako Lp(a) test kit is based on the TIA methodology.

When a sample is mixed with the Buffer and the Antibody, Lp(a) in the sample combines specifically with anti-human lipoprotein(a) antibodies in the reagent to yield an insoluble aggregate that causes turbidity. The degree of turbidity can be measured optically and is proportional to the amount of Lp(a) in the sample.

Precision studies indicate acceptable values can be obtained on a day to day basis. The minimum detectable level of this method is estimated to be 0.3 mg/dL. The Wako Autokit Lp(a) assay had determined to be linear to 100 mg/dL.

Ordering Information

Calibrator

Control